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Kostakis Ioannis

Assistant Professor, Department of Pharmaceutical Chemistry

FULL CV  

Education

  • 1998: Degree in Pharmacy, School of Pharmacy, University of Athens.
  • 2000: MsC in Pharmaceutical Chemistry, School of Pharmacy, University of Athens.
  • 2005: PhD in Pharmaceutical Chemistry, School of Pharmacy, University of Athens.
  • 2005-2007: Post-doctoral research, School of Pharmacy, University of Athens.
  • 2007: Post-doctoral research, (Groupe de Chimie Pharmaceutique, Universite΄ de Rouen, UFR Medecine-Pharmacie).

Research topics

  • Design and synthesis of novel pharmacologically active molecules emphasizing to anticancer and antiviral acting compounds.

List of recent publications

  • Design, Synthesis and Antiproliferative Activity of Some Novel Aminosubstituted Xanthenones, Able to Overcome Multidrug Resistance Towards MES-SA/Dx5 Cells.
    I. K. Kostakis, R. Tenta, N. Pouli, P. Marakos, A.-L. Skaltsounis, H. Pratsinis, D. Kletsas. Bioorg. Med. Chem.Let., 2005, 15, 5057-5060.
  • Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: A new class of cytotoxic compounds.
    C. Hadjipavlou, I. K. Kostakis, N. Pouli, P. Marakos, H. Pratsinis and D. Kletsas. Bioorg. Med. Chem.Let., 2006, 16, 4822-4825.
  • Design, Synthesis and Evaluation of the Antiproliferative Activity of a Series of Novel Fused Xanthenone Aminoderivatives in MDA-MB-231 Breast Cancer Cells
    V. Giannouli, I.K. Kostakis, N. Pouli, P. Marakos, O.Ch. Kousidou, G.N. Tzanakakis and N.K. Karamanos. J. Med. Chem., 2007, 50, 1716-1719.
  • Rapid Synthesis of 2,3-disubstituted-quinazolin-4-ones enhanced by microwave-assisted decomposition of formamide.
    I. K. Kostakis, A. Elomri, E. Seguin, M. Iannelli, T. Besson. Tet. Lett., 2007, 48, 6609-6613 
  • Synthesis and free radical scavenging activity of some new spiropyranocoumarins.
    V. Panteleon, I. K. Kostakis, P. Marakos, N. Pouli, I. Andreadou. Bioorg. Med. Chem. Lett., (2008), 18, 5781-5784.

Contact

 

Kostakis Ioannis
School of Pharmacy
Division of Pharmaceutical Chemistry
Panepistimiopolis- Zografou 157 71
Athens- Greece
Tel: 210 7274212, 2107274184  Fax: 210 727-4747
E-mail: ikkostakis[at]pharm.uoa[dot]gr