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 Mikros Emmanuel 

 Professor, Department of Pharmaceutical Chemistry

Research Group Webage

FULL CV

 

Education

  • 1988:   Ph.D.        (Organic Chemistry)  University PARIS XI,  Orsay, France

  • 1984:   M.Sc.       (Organic Chemistry)  University  PARIS XI,  Orsay, France

  • 1983:   Diploma     (Chemistry) University of Athens 

 Research topics

  • Molecular Structure Analysis of biologically active molecules using N.M.R. spectroscopy and Molecular Calculations:

    • Ligand-Protein Interactions monitored by NMR Spectroscopy and Molecular Modeling
    • Peptides and Natural products structural studies using 2D NMR spectroscopy and Molecular Modeling
    • Structure Based Drug Design, In Silico screening
    • NMR based Metabonomics

Distinctions

 Fellowships - Scholarships

  • DAAD (Germany) 
1996
  • Marie Curie Fellowship
1994
  • CIES (France) 
1993
  • ΙΚΥ (Greece) 
1985-88

 

 List of recent publications

  • Discovery and optimization of a selective ligand for the Switch/Sucrose Non-Fermenting-related bromodomains of Polybromo protein-1 by the use of virtual screening and hydration analysis. V Myrianthopoulos, N Gaboriaud-Kolar, C Tallant, M Hall, S Grigoriou, P Brownlee, O Fedorov, C Rogers, D Heidenreich, M Wanior, N Drosos, N Mexia, P Savitsky, T Bagratuni, E Kastritis, E Terpos, P Filippakopoulos, S Müller, A-L Skaltsounis, J Downs, S Knapp, E Mikros,
    J. Med. Chem., 2016, 59 8787–8803 

  • Heterocovariance Based Metabolomics as a Powerful Tool Accelerating Bioactive Natural Product Identification N Aligiannis M Halabalaki E Chaita, E Kouloura, A Argyropoulou, D Benaki, E Kalpoutzakis, A Angelis, K Stathopoulou, S Antoniou M Sani, V Krauth, O Werz, B Schutz, H Schafer, M Spraul, E Mikros, LA. Skaltsounis
    Chemistry Select 2016, 1, 2531 – 2535 

  • Structure of eukaryotic purine/H+ symporter UapA suggests a role for homodimerization in transport activity Y Alguel, S Amillis, J Leung, G Lambrinidis, S Capaldi, N.J Scull,. G Craven,. S Iwata, A . Armstrong, E Mikros, G Diallinas, A.D Cameron, Byrne, B.
    Nature Communications, 2016 

  • Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation V Myrianthopoulos, PF Cartron, Z Liutkevičiūtė, S. Klimašauskas, D. Matulis, C. Bronner, N. Martinet, E. Mikros,
    European Journal of Medicinal Chemistry, 2016, 114, 390-396 

  • NMR Studies of Inborn Errors of Metabolism S Kostidis, E Mikros.
    eMagRes. 2015, 4, 57-68. 

  • 1H NMR Study on the Short- and Long-Term Impact of Two Training Programs of Sprint Running on the Metabolic Fingerprint of Human Serum A Pechlivanis, S Kostidis, P Saraslanidis, A Petridou, G Tsalis, K Veselkov, E Mikros, V Mougios, GA Theodoridis.
    J. Proteome Res. 2013, 12, 470–480 

  • 1H NMR-based metabonomics approach in a rat model of acute liver injury and regeneration induced by CCl4 administration A Zira, S Kostidis, S Theocharis, F Sigala, SB Engelsen, I Andreadou, E Mikros.
    Toxicology, 2013, 303 115–124  

Contact

   
Professor Mikros Emmanuel
University of Athens
Faculty of Pharmacy
Department of Pharmaceutical Chemistry
Panepistimioupoli-Zografou
157 71 Athens
GREECE
Tel.: +30 210 7274813 Fax.: +30 210 7274747
e-mail: mikros[at]pharm.uoa[dot]gr