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 Pouli Nicole

Professor, Department of Pharmaceutical Chemistry

FULL CV

 

Education

  • PhD in Pharmaceutical Chemistry. Athens University, Greece, 1988. In my thesis entitled "Pyrethroids: Design and synthesis of some new compounds" the synthesis, identification and application of some substituted cyclopropanecarboxylic acid esters, oxime ethers and carbamic acid esters is described.
  • BSc in Pharmacy. Department of Pharmacy, Athens University, Greece, 1982.
  • High School Certificate. 3rd Corfu High School, Greece, 1978.

 Research topics

  •  Synthesis and study of structure-activity relationships of some new compounds with potential antiviral or anticancer activity: nucleoside derivatives, DNA-intercalators, enzyme inhibitors etc. Design and synthesis of centrally active compounds for the treatment of neurodegenerative diseases

 List of recent publications

  • Synthesis and Pharmacological Evaluation of Novel Adenine−Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents. N. Lougiakis, A. Papapetropoulos, E. Gikas, S. Toumpas, P. Efentakis, R. Wedmann, A. Zoga, Z. Zhou, E. K. Iliodromitis, A.-L. Skaltsounis, M. R. Filipovic, N. Pouli, P. Marakos, I. Andreadou J. Med. Chem. (2016) 59 (5), 1776–1790.

  • Novel nucleoside analogues targeting HCV replication through an NS5A-dependent inhibition mechanism N. Lougiakis, E. Frakolaki, P. Karmou, N. Pouli, P. Marakos, V. Madan, R. Bartenschlager, N. Vassilaki, Chemical Biology and Drug Design (2017) 90, 352-367

  • Synthesis and antiproliferative activity of new pyrazolo[3,4-c]pyridines. E.-S. Gavriil, N. Lougiakis, N. Pouli, P. Marakos, A.-L. Skaltsounis, S. Nam, R. Jove, D. Horne, K. Gioti, H. Pratsinis, D. Kletsas, R. Tenta. Medicinal Chemistry, (2017) 13(4), 365 - 374.

  • Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter N. Lougiakis, E.-S. Gavriil, M. Kairis, G. Sioupouli, G. Lambrinidi, D. Benaki, E. Krypotou, E. Mikros, P. Marakos, N. Pouli, G. Diallinas Bioorg. Med. Chem., (2016) 24, 5941-5952.

  • The discovery of new cytotoxic pyrazolopyridine derivatives V. Giannouli, N. Lougiakis, I. K. Kostakis, N. Pouli, P. Marakos, A.-L. Skaltsounis, S. Nam, R. Jove, D. Horne, R. Tenta, H. Pratsinis, D. Kletsas Bioorg. Med. Chem. Lett., (2016) 26, 5229-5233.

Contact

 
Nicole Pouli
Associate Professor
University of Athens
Faculty of Pharmacy
Department of Pharmaceutical Chemistry
Panepistimioupoli-Zografou
157 71 Athens
GREECE
Τel: 210 727-4185  Fax: 210 727-4747
E-mail: pouli[at]pharm.uoa[dot]gr