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Dokoumetzidis Aristeidis

Assistant Professor, Department of Pharmaceutical Technology

 

Previous employments

2008-2009

Lecturer in Biopharmaceutics and Pharmacokinetics, School of Pharmacy of Queen’s University Belfast, UK.

2003-2008

Research Fellow at the School of Pharmacy and Pharmaceutical Sciences of the University of Manchester (UK).

 

Education 

2002

PhD, School of Pharmacy of the University of Athens 

1999

MSc in Physics, University of Athens

1996

Physics Degree, University of Athens

 Research interests

  • Applications of pharmacometrics in drug development

  • Pharmacokinetic / pharmacodynamic modelling

  • Development of new methodology in Pharmacometrics

  • Clinical pharmacokinetics

  • Quantitative Systems Pharmacology

Esteem factors

Editorial Advisory Board of the Journal of Pharmacokinetics and Pharmacodynamics

 

Selected recent publications 

 

  1. Dokoumetzidis A., Aarons L. Propagation of population pharmacokinetic information using a Bayesian approach: comparison with meta-analysis. J Pharmacokinet Pharmacodyn 32: 401-418 (2005).

  2. Dokoumetzidis A., Kalantzi L., Fotaki N. Predictive models for oral drug absorption: From in silico methods to integrated dynamical models. Expert Opin. Drug Metab. Toxicol. 3: 491-405 (2007).

  3. Dokoumetzidis A., Aarons L. Proper lumping in systems biology models. IET Systems Biology 3:40-51 (2009).

  4. Dokoumetzidis A., Macheras P. Fractional kinetics in drug absorption and disposition processes. J. Pharmacokinet Pharmacodyn. 36: 165-178 (2009).

  5. Dokoumetzidis A., Magin R., Macheras P. Fractional kinetics in multi-compartmental systems. J. Pharmacokinet Pharmacodyn. 37: 508-524 (2010).

  6. Nalda-Molina R., Dokoumetzidis A., Charkoftaki G., Dimaraki E., Margetis K., Archontaki H., Markantonis S., Boutos N., Sakas D., Vryonis E., Skoutelis A., Valsami G. Pharmacokinetics of Doripenem in Cerebrospinal Fluid of patients with non-inflamed meninges. J. Antimicrob Chemother 67:1722-1799 (2012).

  7. Pippa N, Dokoumetzidis A, Pispas S, Demetzos C. The interplay between the rate of release from polymer grafted liposomes and their fractal morphology. Int J Pharm. 465:63-69 (2014).

  8. Kechagia IA, Dokoumetzidis A. Development of a paediatric population pharmacokinetic model for valacyclovir from literature non-compartmental values originating from sparse studies and Bayesian priors: a simulation study. J Pharmacokinet Pharmacodyn. 42:237-250 (2015).

  9. Kechagia IA, Kalantzi L., Dokoumetzidis A. Extrapolation of enalapril efficacy from adults to children using PKPD modelling. J Pharm Pharmacol 67:1537-1545 (2015).

  10. Kechagia IA, Kalantzi L., Dokoumetzidis A. Extrapolation of valacyclovir posology to children based on pharmacokinetic modelling. Pediatr Infect Dis J34:1342-1348 (2015).

Contact details

Aris Dokoumetzidis
School of Pharmacy
University of Athens
Athens 15771
Greece
Tel: +30 210 727-4122, Fax: +30 210 727-4027

E-mail: adokoum[at]pharm.uoa[dot]gr