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Dimitrios M. Rekkas

Associate Professor of Pharmaceutical Technology

Brief presentation of technologies and research activities

Quality By Design

 

 

Education

  • B.Pharm.University of Athens,Greece,
  • PhD in Pharmaceutical Technology,University of Athens,Greece.
  • MSc in Total Quality Management,Sheffield Hallam University,UK.      

 

Research-Teaching -Writing interests

 

  • Pharmaceutical Technology
  • Industrial Pharmacy
  • Dosage Form Design
  • Experimental Design
  • Statistical Process Control
  • Quality Control
  • Quality Assurance
  • Total Quality Management
  • Quality by Design (QbD)

 

Other Activities

  • Invited speaker on current Good Manufacturing Practices for Pharmaceutical Products, Industrial Pharmacy, Experimental Design, Total Quality Management, Quality Control and Assurance, Dosage Form Design, Quality by Design.
  • Erasmus Socrates Coordinator.
  • Visiting Scientist at the Food and Drug Administration (FDA).
  • Vice President of the Management Committee of the European Program COST 865- Bioencapsulation.
  • Invited Professor at the School of Pharmacy, University of Vienna, Austria, University of Parma and University of Ferrara, Italy
  • Scientific coordinator of an e-learning program on Total Quality Management, UoA.
  • Member of the international affairs committee of the University of Athens.
  • Director of Pharmaceutical Technology Laboratory.
  • Director of the Pharmaceutical Technology division
  • Member of the SimInhale Cost Action MP1404 on inhaled medicines.

 

Publications

Papers

  • Politis S.N., Rekkas D.M., Pelletization Processes for Pharmaceutical Applications: A Patent Review. Recent Patents on Drug Delivery and Formulation 5,1,61-78,2010.

  • Korakianiti E., Rekkas D.M, Statistical thinking and knowledge management for quality-driven design and manufacturing in pharmaceuticals.Pharmaceutical Research 28,1465-79,2011.

  • Politis S.N., Rekkas D.M., The Evolution of the manufacturing science and the pharmaceutical industry.Pharmaceutical Research 28,1779-1781,2011.

  • Politis S.N., Rekkas D.M. Recent advantages in pulsatile oral drug delivery systems. Recent Patents on Drug Delivery and Formulation 7,2,87-98,2013.

  • Belotti S., Rossi A., Colombo P., Bettini R., Rekkas D., Politis S., Colombo G.,Balducci AG., Buttini F., Spray dried amikacin powder for inhalation in cystic fibrosis patients: A quality by design approach for product construction.International Journal of Pharmaceutics 471,1-2,507-515,2014.

  • Belotti S., Rossi A., Colombo P., Bettini R., Rekkas D., Politis S., Colombo G., Balducci AG., Buttini F., Spray-dried amikacin sulphate powder for inhalation in cystic fibrosis patients: The role of ethanol in particle formation.European Journal of Pharmaceutics and Biopharmaceutics 93,165-172,2015.

  • Politis S.N, Colomblo P, Colombo G, Rekkas D.M. Design of experiments (DoE) in pharmaceutical development.Drug Development and Industrial Pharmacy 43,6,889-901,2017.

  • Karatzas AA, Politis SN, Rekkas DM.Development of rapidly dissolving pellets within the Quality by Design approach.Drug Development and Industrial Pharmacy 43,5,770-779,2017.

  • Politis S.N, Rekkas D.M.Development of a fast, lean and agile direct pelletization process using experimental design techniques. Drug Development and Industrial Pharmacy 43,4,545-557, 2017.

Book

  • “Total Quality Management” T. Georgaki, K. Kouroupi, S. N. Politis and D.M. Rekkas, Athens 2010, Sideris Publications.

Patents

  • Rekkas D.M., Dallas P., Paterakis P., Hot melt direct pelletization process using a fluidized bed rotor granulator. GR1004855
  • Dallas P ., Rekkas D.M., Georgaki D. Pharmaceutical formulation for the transdermal administration of Ketotifen. GR1004995.
  • Rekkas D.M., Politis S.N. Hot melt direct pelletization for the production of modified release spheroids. GR20100100130
  • Rekkas D.M., Papamichail M., Politis S.N., Novel Pharmaceutical and Cosmetic Emulsions GR20120100449
  • Rekkas D.M., Politis S.N., Karatzas A., Manufacturing process for the preparation of fast disintegrating effervescent pellets, granules and or mixtures thereof GR1008366.

 

Contact Details

Dimitrios M.Rekkas

School of Pharmacy

University of Athens

Athens, 15771

Greece

Tel: +30-210-7274023

Fax: +30-210-7274027

E-mail: rekkas[at]pharm.uoa[dot]gr