Aligiannis Nektarios

Assistant Professor,  Department of Pharmacognosy and Natural Product Chemistry

FULL CV  

Education

• Bachelor in Pharmacy, University of Athens, Greece (1995)

• M.Sc. in Pharmacognosy, University of Athens, Greece (1997)

• Ph.D in Pharmacognosy, University of Athens, Greece (2002)

• PostDoc  in Pharmacology, University of Besancon, France  (2004)

Research topics

• Phytochemical analysis of plants of the Greek, Mediterranean flora as well as plants from Mongolia.

• Synthesis of natural products derivatives (flavonoids, benzofurans, anthracyclines, chalcones, diarylpropanes, stilbenes)

• Biological evaluation of natural products and semi-synthetic derivatives for their antioxidant, bleaching and antiaging properties.

• Exploitation of bioactive natural products as pharmaceuticals and nutraceuticals.

• Applications of 1D and 2D NMR, HPLC, MPLC, CC and LC-MS in Natural Products Chemistry.

• Recording and assessing information of folk medicine

Distinctions

• 1996: Award for graduate studies in “Pharmacognosy of biologically active natural products”. Source: State Scholarships Foundation.

• 2000: Awarded the “Best Performance” prize for M.Sc. studentship by the Hellenic society of the Pharmaceutical Industry.

List of recent publications

• “Sesquiterpene lactones from Staechelina fruticosa L” Kotsos M.P.; Aligiannis, N.; Myrianthopoulos V.; Mitakou S.; Skaltsounis A.L. J. Nat. Prod. 2008, 71, 847-851.

• “Effects of Leguminosae family plant extracts and polyphenolic fractions on topoisomerase I-induced nicking of DNA” Spanou C., Aligiannis N., Skaltsounis A.L., Kouretas D. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 2008, 22, 336-338.

• “Biologically active triterpenoids from Cephalaria ambrosioides” Pasi S.; Aligiannis, N.; Pratsinis H., Skaltsounis A.L.; Chinou I. Planta Med. 2008, 75, 163-167.

• “Triterpenoids from Eucalyptus camaldulensis Dehnh. Tissue Cultures” Tsiri D., Aligiannis N., Graikou K., Spyropoulos C., Chinou I. Helvetica Chimica Acta 2008, 91, 2110-2114.

• “Antioxidant and chemopreventive properties of polyphenolic compounds derived from Greek legume plant extracts” Spanou C., Bourou G., Dervishi A., Aligiannis N., Angelis A., Komiotis D., Skaltsounis A.L., Kouretas D. J. Agric. Food Chem. 2008, 56, 6967-8276.

• “Ebenfurans IV-VIII from Onobrychis ebenoides: evidence that C-prenylation is the key determinant of the cytotoxicity of 3-formyl-2-arylbenzofurans” Halabalaki M., Alexi X., Aligiannis N., Alexis M.N., Skaltsounis A.-L. J. Nat. Prod. 2008, 71, 1934-1937.

• “Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells”. Kassi E., Sourlingas T.G., Spiliotaki M., Papoutsi Z., Pratsinis H., Aligiannis N., Moutsatsou P. Cancer Investigation 2009, 27, 723-733.

• “Chemical composition and antimicrobial activity of the essential oils of four Ocimum species growing in Tanzania”. Runyoro D., Ngassapa O., Vagionas K., Aligiannis N., Graikou K., Chinou I. Food Chemistry 2010, 119, 311-316. 

• “Hydrostatic countercurrent chromatography and ultra high pressure LC: Two fast complementary separation methods for the preparative isolation and the analysis of the fragrant massoia lactones” Urbain A., Corbeiller P., Aligiannis N., Halabalaki M., Skaltsounis A.-L. J. Separation Science 2010, 33 (9), 1198-1203

• “Influence of potent antioxidant leguminosae family plant extracts on growth and antioxidant defense system of Hep2 cancer cell line” Spanou C., Stagos D., Aligiannis N., Kouretas D. J. Medicinal Food 2010, 13 (1), 149-155

• “The raputindoles: Novel cyclopentyl bisindole alkaloids from raputia simulans”  Vougogiannopoulou K., Fokialakis N., Aligiannis N., Cantrell C., Skaltsounis A.-L. Organic Letters 2010, 12, 1908-1911.

Contact

Dr. Aligiannis Nektarios

Division of Pharmacognosy and Chemistry of Natural Products 

Department of Pharmacy, University of Athens

Panepistimioupolis Zografou 15 771

Athens, Greece

Tel: ++30 10 727-4757, Fax: ++30 10 727-4594

E-mail: aligiannis[at]pharm.uoa[dot]gr