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 Fokialakis Nikolaos

Assistant Professor,  Department of Pharmacognosy and Natural Product Chemistry



  • Bachelor in Pharmacy, University of Athens, Greece (1998)
  • M.Sc. in Pharmacognosy, University of Athens, Greece (2000)
  • Ph.D in Pharmacognosy, University of Athens, Greece (2004)
  • PostDoc, ARS, USDA, Oxford, MS, USA  (2004-2006)

Research topics

  • Phytochemical analysis of plants of the Greek, Mediterranean flora as well as plants from Oceania and Amazonia.
  • Chemical investigation of edible mushrooms and filamentous fungi
  • Synthesis of natural products (flavonoids, acridones, coumarins,)
  • Biological evaluation of natural products and semi-synthetic derivatives.
  • Exploitation of bioactive natural products as pharmaceuticals, nutraceuticals, and biopesticides.
  • Applications of 1D and 2D NMR, HPLC, MPLC, CC and LC-MS in Natural Products Chemistry.


  • 2010: Arthur Neish Award of the Phytochemical Society of North America (PSNA)
  • 2006 : Research starter Grant of the American Society of Pharmacognosy
  • 2001: Award for graduate studies in “Pharmacognosy of biologically active natural products”. Source: State Scholarships Foundation.
  • 1999: Travel grant of AFERP (5th Joint Meeting of ASP, GA, AFERP, PSE Amsterdam 1999)

List of recent publications

  • The raputindoles: Novel cyclopentyl bisindole alkaloids from Raputia simulans. Vougogiannopoulou, K., Fokialakis, N., Aligiannis, N., Cantrell, C., Skaltsounis, A.-L. Organic Letters 12, 2010, 1908-1911
  • Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing? Christodoulou M.S, Thomas A., Poulain S, Vidakovic M., Lahtela-Kakkonen M., Matulis D., Bertrand P., Bartova E., Blanquart C., Mikros E., Fokialakis N., Daniele Passarella D., Benhida R. and Martinet N. MedChemCommun, 2014, 5, 1804-1820.
  • Novel Conformationally Constrained Pyrazole Derivatives as Potential Anti-Cancer Agents. Kasiotis Κ., Tzanetou Ε.Ν., Stagos D., Fokialakis N., Koutsotheodorou E., Kouretas D., Haroutounian S.A. Z. Zeitschrift fur Naturforschung B, 2015; 70(9). DOI:10.1515/znb-2015-0053.
  • Antioxidant Properties of the Wild Edible Mushroom Lactarius salmonicolor. Athanasakis G., Aligiannis N., Gonou-Zagou Z., Skaltsounis A.L and Fokialakis N. Journal of Medicinal Food, 2013, 16: 760-764.
  • Submerged Fermentation of the Edible Mushroom Pleurotus ostreatus in a Batch Stirred Tank Bioreactor as a Promising Alternative for the Effective Production of Bioactive Metabolites. Papaspyridi L.M., Aligiannis N, Topakas E, Christakopoulos P, Skaltsounis A.L. and Fokialakis N* Molecules, 2012, 17, 2714-2724.


Dr. Nikolas Fokialakis

Division of Pharmacognosy and Chemistry of Natural Products 

Department of Pharmacy, University of Athens

Panepistimioupolis Zografou 15 771

Athens, Greece

Tel: ++30 10 727-4727, Fax: ++30 10 727-4594

E-mail: fokialakis[at]pharm.uoa[dot]gr