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Magiatis Prokopis

Assistant Professor,  Department of Pharmacognosy and Natural Product Chemistry

FULL CV

Education

  • Bachelor in Pharmacy, University of Athens, Greece (1994)
  • M.Sc. in Pharmacognosy, University of Athens, Greece (1997)
  • Ph.D in Pharmacognosy, University of Athens, Greece (2000)
  • PostDoc, Insitut Curie, Paris, France (2001)

Research topics

  • Isolation of compounds with pharmaceutical and nutraceutical interest from natural sources. Search of new lead compounds of plant and marine origin from Greek and Mediterranean flora and sea. Investigation of plants from tropical regions.
  • Natural products structure determination using modern NMR techniques, Mass spectrometry and Molecular Modeling.
  • Design and synthesis of new molecules with pharmacological interest (kinase inhibitors, neuroprotective agents, antitumor, antibiotics, estrogen/antiestrogen) based on a natural product core; structure-activity relationships, optimization of lead compounds.
  • Treatment of agricultural wastes for the large scale production of high added value natural products
  • Essential oils, volatile, flavor and aroma constituents

Distinctions

  • Egon Stahl Award (Silver). Top scientist in Europe under 40 years old for 2009 in the fields of Parmacognosy, analytical phytochemistry, pharmaceutical biology and synthesis of natural products. Source: Society of Medicinal Plants and Natural Product Research (GA)
    (Award Lecture Geneva 17 August 2009)
  • Award of American Society of Pharmacognosy (5th Joint Meeting of ASP, GA, AFERP, PSE Amsterdam (1999)
  • st medal of performance and morals. Source: U. of Athens (1994)
  • Honorary diploma for special academic performance (1st prize). Source: 7nth Panhellenic Pharmaceutical Congress. (1994)
  • Honor in panhellenic examination in mathematics. Source: Greek Mathematics Society. (1987)

List of recent publications

  • “GSK-3 selective inhibitors derived from Tyrian purple indirubins Meijer, L.; Skaltsounis, A.L.; Magiatis, P.; Polychronopoulos, P.; Knockaert, M.; Leost, M.; Ryan, X.P.; Vonica, C.A.; Brivanlou, A.; Greengard, P et al. Chemistry and Biology 2003, 10, 1255-1266
  • “7-bromo-indirubins induce caspase-independent cell death” Ribas, J.; Bettayeb, K.; Ferandin, Y.; Knockaert, M.; Totzke, F.; Schächtele, C.; Mester, J.; Polychronopoulos, P.; Magiatis, P.; Skaltsounis, A.L.; Boix, J.; Meijer, L. Oncogene 2006, 25, 6304-6318.
  • “In vitro and in vivo activity of chios mastic gum extracts and constituents against Helicobacter pylori” Paraschos S., Magiatis P., Mitaku S., Petraki K., Kaliaropoulos A., Maragoudakis P., Mentis A., Sgouras D., Skaltsounis A.-L. Antimicrobial Agents Chemotherapy 2007, 51, 551-559
  • “Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease” J. Lekakis, L. Rallidis, I. Andreadou, G. Vamvakou, G. Kazantzoglou, P. Magiatis, A. L. Skaltsounis, D. Kremastinos. European Journal of Cardiovascular Prevention and Rehabilitation 2005, 12, 596-600.
  • "The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits” I. Andreadou, E. Iliodromitis, E. Mikros, M. Constantinou, A. Agalias, P. Magiatis, A. Skaltsounis, D. Kremastinos. J. Nutrition 2006, 136, 2213-2219
  • Malassezia furfur isolated from seborrheic dermatitis skin lesions produces the AhR ligands malassezin and indole[3,2-b]carbazole” Gaitanis, G.; Magiatis, P.; Stathopoulou, K.; Velegraki, A.; Bassukas, I.; Alexopoulos, E.; Skaltsounis, A.L Journal of Investigative Dermatology 2008, 128, 1620-1625.

Contact

Prokopios Magiatis
Department of Pharmacognosy and Natural Products Chemistry
Faculty of Pharmacy
University of Athens
Panepistimioupolis Zografou 15 771
Athens, Greece
Tel: ++30 10 727-4052, -4582 Fax: ++30 10 727-4594
E-mail: magiatis[at]pharm.uoa[dot]gr