RESEARCH FIELDS

Research performed includes Medicinal Chemistry, Pharmaceutical Analysis, Pharmacology, Pharmacognosy and Chemistry of Natural Products, Pharmaceutical Technology, Biopharmaceutics and Clinical Pharmacy.

A general description is provided below:

Medicinal Chemistry

Design and synthesis of bioactive compounds:Marakos Panagiotis, Pouli Nicole, Tsotinis Andrew, Kourounakis Angeliki, Zoidis Grigoris, Kostakis Ioannis, Papanastasiou Ioannis, Lougiakis Nikolaos, Kolocouris Antonios

Tsotinis, melatonin receptors' ligands, trypanocidals, cytotoxic compounds, antivirals
Papanastasiou, trypanocidals, antivirals, antitubercular, antiviral, melatonergic, cannabinergic and antiproliferative, adamantane derivatives
Κostakis, anticancer, antiviral, antifungal, neurodegenerative diseases, kinases, bromodomains, mitochondrial-targeted compounds (polyphenols, coumarins, xanthones, indoles, carbazoles, acridines, aza-acridines, pyrimidines, stavrosporins etc)
Lougiakis, antiproliferative derivatives, kinase inhibitors, antiviral agents, purine isosters, nucleosides, cellular senescence biomarkers, adenosine receptors probes
Kolocouris, compounds targeting influenza A M2 proton channel, tuberculosis MmpL3 transporter, purinergic P2X7 ATP channel (against Parkinson), soluble epoxide hydrolase (against diabetes), adenosine receptor (in collaboration), bio-conjugates (in collaboration)
Marakos, Pouli, antiproliferative derivatives, kinase inhibitors, antiviral agents, purine isosters, nucleosides, cellular senescence biomarkers, adenosine receptors probes
Kourounaki, design, synthesis and pharmacological evaluation (in vitro/in vivo) of bioactive molecules (antiinflammatory/antioxidant/antihyperlipidemic/cytoprotective) with an emphasis on multi-target drug design for multifactorial diseases such as atherosclerosis or neurodegeneration

Computational drug design, computational organic chemistry, biophysics: Mikros Emmaneul, Kolocouris Antinios, Myrianthopoulos Vasileios, Lambrinidis George

Pharmaceutical Analysis

Αnalysis of drugs, and bioactive compounds in pharmaceutics and biological fluids: Panderi Irene, Mikros Emmanuel, Dotsikas Ioannis, Loukas Ioannis

NMR spectroscopy, metabolomics: Mikros Emmanuel, Benaki Dimitra

Mass Spectrometry, omics: Panderi Irene, Dotsikas Ioannis, Loukas Ioannis