PHARMACOGNOSY II

Compulsory / Teaching hours per week: 5 / Assessment: final exam at the end of each term or September/ Credits: 6 

Teachers:

Sofia Mitakou, professor
Eleni Skaltsa, professor
Αlexios Leandros Skaltsounis

Course site (e-class): eclass.uoa.gr/modules/document/

Topics:

    • Alkaloids: Introduction, physicochemical properties, detection, extractions, pharmacological activities, biosynthesis.
    • Ornithine and lysine derivatives: tropane alkaloids of Solanaceae and Erythroxylaceae, pyrrolizidine alkaloids, nicotinic acid derivatives, indolizidine, quinolizidine, piperidine alkaloids,  anthranilic acid derivatives, terpene and steroide alkaloids, histidine derivatives, purine alkaloids. 
    • Phenylalanine and tyrosine alkaloids: Phenylethylamines, simple isoquinolines, curare, morphinane alkaloids, phenethylisoquinolines, monoterpene isoquinolines,  Amaryllidaceae alkaloids. 
    • Tryptophan alkaloids: tryptamines, β-carbolines, ergoline derivatives, monoterpene indole alkaloids, alkaloids of Cinchona and Vinca, Ellipticin, Camptothecin. 
    • Terpenes and steroids: essential oils, pyrethroids, iridoids, sesquiterpene lactones, diterpenes, triterpenes, modified triterpenes: limonoids, quassinoids, brassinoids, saponins, sterols, steroids, N containing glycosides, glycerosides, sterols, cardiotonic glycosides, Carotenoids
    • Oleoresins, Balsams.