DRUG METABOLISM

(Εlective / Teaching hours per week: 3 / Laboratory hours per week: 0/Assessment: Final exam at the end of each term and/or in September and optional term-paper/ Credits: 3)

Teachers:

Angeliki Kourounakis, Associate Professor

Course site (e-class): eclass.uoa.gr/courses/PHARM153/

Topics:

    • Drug metabolic pathways. Biotransformation reactions.
    • Molecular mechanisms of Drug metabolism. Enzymes involved.
    • Endogenous and Exogenous Factors influencing Drug Metabolism.
    • Genetic polymorphisms of Drug metabolising enzymes and their role in Drug response.
    • Induction and inhibition of Drug metabolism.
    • Drug-Drug and Drug-Food interactions.
    • Application of Drug metabolism in Drug Design.