MELLIOU ELENI

Laboratory Teaching Staff

Section of Pharmacognosy & Chemistry of Natural Products

 

Education

  • 11/2005: Ph.D in Pharmacognosy and Natural Products Chemistry (Faculty of Pharmacy, National and Kapodistrian University of Athens). Degree: Excellent. Ph.D. thesis title: Chemical analysis and biological activity of honey, propolis and royal jelly.
  • 7/2002: M.Sc. in “Pharmacognosy of Bioactive Natural products” (Dept. of Pharmacy, National and Kapodistrian University of Athens). Degree: Excellent. Dissertation title: “Phytochemical investigation of the edible plant of Crete diet Cichorium spinosum, Compositae”
  • 9/2000: B.Sc in Chemistry, National and Kapodistrian University of Athens, Degree: Good
  • 4/1996 : B.Sc in Food Science/Technology, Degree: Very good, Technological Institute of Athens

Teaching

Undergraduate courses/labs: 

  • ANALYTICAL CHEMISTRY I
  • ANALYTICAL CHEMISTRY II

Research topics

  • Development of analytical methods (qNMR, LCMS, colorimetric applications) for the quantitation of bioactive ingredients in herbal medicinal products and foods. 
  • Isolation of compounds with pharmaceutical and nutraceutical interest from natural sources. Focus on olive oil and olive products.  
  • Natural products structure elucidation using modern NMR techniques, Mass spectrometry and Molecular Modeling. 
  • Essential oils, volatile, flavor and aroma constituents

Distinctions

  • 4/2018-today: World Olive center for health (President)
  • 9/2014-6/2016: Affiliate Faculty, Virginia Commonwealth University, School of Medicine, Department of Physiology and Biophysics
  • 10/2013-12/2013: Visiting scholar, University of California, Davis-Olive Center
  • 5/2011-11/2011, Visiting scholar, University of California, Davis-Department of Food Science
  • 2/2018: 1st award for research on olive products in OLIVE-CHALLENGE (source: SEVITEL)
  • 2/2016: ARISTOLEO test: 1st Award for the best innovation in Greece for 2015 (Prize: 15,000 €, Source: Greek Industries Association/Eurobank)
  • 2013: Award for the scientific contribution to the chemical study of Throuba Thassos table olives. Source: Agricultural Cooperative of Thassos
  • 2012: Best Poster award: “Malassezia species produce a mixture of the most powerful AhR ligands in human skin” 1st Congress of Pharmaceutical Sciences (Athens)
  • 2005: Travel Grant from the Society of Medicinal Plant Research 53rd Annual Congress Florence 21-25 August 2005
  • 2005: Best poster award (650 posters from 75 countries) from the Society of Medicinal Plant Research 53rd Annual Congress Florence 21-25 August 2005. “Advances in the chemistry and bioactivity of royal jelly” E. Melliou, I.Chinou.
  • 2000-2002: Scholarship for postgraduate studies in “Pharmacognosy of biologically active natural products”. Source: State Scholarships Foundation (by examination rank 1st).
  • 1995, 1996, 1997, 1998, 1999, 2000, 2001: Academic scholarship (by examination rank). Source: Foundation “Kantari” 
  • 1992-1993: Academic performance scholarship. Source: Naval Insurance Organization (by examination rank 1st).

Recent publications

  • “S‐(E)‐Elenolide: a new constituent of extra virgin olive oil” A. Rigakou,  P. Diamantakos, E. Melliou and P. Magiatis,  Journal of the Science of Food and Agriculture, 2019, 99, 5319-5326. 
  • “Quantitation of Oleuropein and Related Phenolics in Cured Spanish-Style Green, California-Style Black Ripe, and Greek-Style Natural Fermentation Olives” R Johnson, E Melliou, J Zweigenbaum, AE Mitchell. Journal of agricultural and food chemistry 2018, 66 (9), 2121-2128. 
  • “Oleocanthalic acid, a chemical marker of olive oil aging and exposure to high storage temperature with potential neuroprotective activity” A. Tsolakou, P. Diamantakos, I. Kalaboki, A. Mena-Bravo, F. Priego-Capote, A. Kaddoumi, E. Melliou, P. Magiatis. Journal of Agricultural and Food Chemistry 2018, 66 (28), 7337-7346
  •  “Effect of Olive Oil Phenolics on Lipidemic Profile and Oxidative Stress in Mice” N. Demertzis, A. Fotopoulou-Stamatelou, S. Gkinis, M. Kyriazi, E. Karalis, G.Th. Papaiwannou, E. Melliou, A. Kourounakis, P. Magiatis, H. S. Black,  M. Rallis.  J Food Nutrition Dietetics 2018, 2(1): 114.
  • Cultivar influence on variability in olive oil phenolic profiles determined through an extensive germplasm survey. H. Miho, C.M. Díez, A. Mena-Bravo, V.S. de Medina, J. Moral, E. Melliou, P. Magiatis, F. Priego-Capote. Food Chemistry 2018, 266, 192-199
  • “Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography–tandem mass spectrometry” V. Sánchez De Medina, H. Miho, E. Melliou, Luque De Castro, P. Magiatis, F. Priego-Capote Talanta, 2017, 162, 24-31. 
  •  “Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial” K Agrawal, E Melliou, X Li, TL Pedersen, SC Wang, P Magiatis, J. Newman. J Functional Foods 2017, 36, 84-93
  •  “Enhancement of Bioactive Phenols and Quality Values of Olive Oil by Recycling Olive Mill Waste Water” K. Kiritsakis, E. Melliou, P. Magiatis,  D. Gerasopoulos. Journal of the American Oil Chemists' Society, 1-9, 2017.
  • “Ultrahigh-Pressure Liquid Chromatography Triple-Quadrupole Tandem Mass Spectrometry Quantitation of Polyphenols and Secoiridoids in California-Style Black Ripe Olives and Dry Salt-Cured Olives” E Melliou, JA Zweigenbaum, AE Mitchell. Journal of Agricultural and Food Chemistry 2015, 63 (9), 2400-2405
  • “Oleokoronal and oleomissional: new major phenolic ingredients of extra virgin olive oil” P. Diamantakos, A. Velkou, K. B. Killday, Th. Gimisis, E.Melliou, P. Magiatis. OLIVAE 2015, 122, 22-35 
  • “Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers” E. Karkoula,  A. Skantzari, E. Melliou, P. Magiatis, Journal of Agricultural and Food Chemistry, 2014, 62, 600-607. 
  • “Isolation of Megaritolactones and Other Bioactive Metabolites from 'Megaritiki' Table Olives and Debittering Water” E. Mousouri, E. Melliou, P. Magiatis. Journal of Agricultural and Food Chemistry 2014, 62, 660-667. 
  • “Direct Measurement of Oleocanthal and Oleacein Levels in Olive Oil by Quantitative 1H-NMR. Establishment of a New Index for the Characterization of Extra Virgin Olive Oils” E. Karkoula,  A. Skantzari, E. Melliou, P. Magiatis, Journal of Agricultural and Food Chemistry, 2012, 60, 11696-1170 

Contact

Postal address: Section of Pharmacognosy and Natural Products Chemistry,
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 71
Athens, Greece
Tel.: +30(210) 727 4052
e-mail: emelliou@pharm.uoa.gr