Skip to main navigation Skip to main content Skip to page footer


Professor, Section of Pharmaceutical Chemistry

Research Group Webage




  • 1988:    Ph.D.        (Organic Chemistry)  Université  PARIS XI,  Orsay,  France
  • 1984:    M. Sc.        (Organic Chemistry)  Université  PARIS XI,  Orsay,  France
  • 1983:    Diploma     (Chemistry) University of Athens


Undergraduate courses/labs: 

  • Inorganic Pharmaceutical Chemistry
  • Organic Spectroscopy
  • Lab Work Pharmaceutical Chemistry
  • Lab Work Pharmaceutical Analysis
  • Drug Design

Graduate courses: 

  • Advanced Medicinal Chemistry
  • Organic Spectroscopy I
  • Organic Spectroscopy II

Research topics
N.M.R. spectroscopy 
Molecular Structure Analysis of biologically active molecules (natural products peptides) and using and 
Structure Based Drug Design, Molecular Simulations, In Silico screening
NMR basedMetabolomics

Distinctions - Fellowships

  • DAAD (Germany)            1996 
  • Marie Curie Fellowship (European)    1994
  • CIES (France)                1993
  • Nat. Found. Sch. (ΙΚΥ Greece)        1985-88
  • Invited Professor
  • Invited Professor University of Vienna, March-May 2017 
  • Invited Professor Institut de Chimie de Nice December 2013

Selected publications

  • 1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues. Grienke U, Foster PA, Zwirchmayr J, Tahir A, Rollinger JM, Mikros E. Sci Rep. (2019), 9:11113.
  • Discovery and optimization of a selective ligand for the Switch/Sucrose Non-Fermenting-related bromodomains of Polybromo protein-1 by the use of virtual screening and hydration analysis." V Myrianthopoulos, N Gaboriaud-Kolar,; C Tallant,; M Hall, ; S Grigoriou,; P Brownlee,; O Fedorov, C Rogers,; D Heidenreich,  M Wanior, N Drosos, N Mexia, P Savitsky, T Bagratuni, E Kastritis, E Terpos, P Filippakopoulos, S Müller, A-L Skaltsounis, J Downs, S Knapp, E Mikros, J. Med. Chem., (2016), 59 8787–8803
  • Structure of eukaryotic purine/H+ symporter UapA suggests a role for homodimerization in transport activity Y Alguel, S Amillis, J Leung, G Lambrinidis, SCapaldi, N.J Scull, G Craven, S Iwata, A Armstrong, E Mikros, G Diallinas, A.D Cameron, Byrne, B. Nature Communications, (2016)
  • Heterocovariance Based Metabolomics as a Powerful Tool Accelerating Bioactive Natural Product Identification N Aligiannis M Halabalaki E Chaita, E Kouloura, A Argyropoulou, D Benaki, E Kalpoutzakis, A Angelis, K Stathopoulou, S Antoniou M Sani, V Krauth, O Werz, B Schutz, H Schafer, M Spraul, E Mikros, LA. SkaltsounisChemistry Select (2016), 1, 2531 – 2535
  • H-1 NMR Metabonomic Analysis in Renal Cell Carcinoma: a Possible Diagnostic Tool Zira, AN; Theocharis, SE; Mitropoulos, D; Migdalis V; Mikros E. J. Prot. Res.  (2010), 9, 4038-4044
  • 1H NMR-Based Metabonomics for the Classification of Greek Wines According to Variety, Region and Vintage – Comparison with HPLC Data.  Anastasiadi, M; Zira, A; Magiatis, P; Haroutounian, S; Skaltsounis, AL; Mikros E; J. Agr. Food. Chem. (2009); 57; 11067-11074
  • An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins; Myrianthopoulos, V; Magiatis, P; Ferandin, Y; Skaltsounis, AL; Meijer, L; Mikros, E; J. Med. Chem.; (2007); 50; 4027-4037
  • Application of nuclear magnetic resonance spectroscopy combined with principal component analysis in detecting inborn errors of metabolism using blood spots: a metabonomic approach; Constantinou, MA; Papakonstantinou, E; Benaki, D; Spraul, M; Shulpis, K; Koupparis, MA; Mikros, E; Anal. Chim. Acta; (2004); 511; 303-312



Professor Mikros Emmanuel
University of Athens
Faculty of Pharmacy
Department of Pharmaceutical Chemistry
157 71 Athens

Tel.: +30 210 7274813 Fax.: +30 210 7274747

e-mail: mikros[at]pharm.uoa[dot]gr