MAGIATIS PROKOPIOS

Associate Professor,  Section of Pharmacognosy and Natural Product Chemistry

FULL CV

 

Education

  • Degree in Pharmacy (7/1994, Department of Pharmacy, U. of Athens). 9.03/10 Excellent
  • Ph.D in Pharmacognosy (3/2000: Faculty of Pharmacy, U. of Athens). Ph. D. thesis title: “Design, synthesis and pharmacological evaluation of derivatives of the natural anticancer alkaloid acronycine”. Excellent.  
  • M.Sc. in “Pharmacognosy of biologically active natural products” (10/1997, Department of Pharmacy, U. of Athens).  Excellent 

Teaching

Undergraduate courses/labs: 

  • PHARMACOGNOSYΙ (E505)
  • PHARMACOGNOSY ΙΙΙ LABS

Graduatecourses: 

  • SPECTROSCOPY ΙΙ (4004)
  • BIOLOGICAL TESTS (4006)
  • APPLICATIONS OF NATURAL PRODUCTS (4009)
  • INTRODUCTION TO GOOD LABORATORY PRACTICE
  • BIBLIOGRAPHIC SEARCH ON SPECIALIZED TOPICS

Research topics

  • -Development of analytical methods (qNMR, LCMS, colorimetric applications) for the quantitation of bioactive ingredients in herbal medicinal products and foods. 
  • -Isolation of compounds with pharmaceutical and nutraceutical interest from natural sources. Focus on olive oil and olive products. Search of new lead compounds from microorganisms, plants and marine organisms. 
  • -Natural products structure elucidation using modern NMR techniques, Mass spectrometry and Molecular Modeling. 
  • -Design and synthesis of new molecules with pharmacological interest (kinase inhibitors, neuroprotective agents, antitumor, antibiotics) based on a natural product core; structure-activity relationships, optimization of lead compounds.
  • -Investigation of natural lead compounds based on plants recorded in historical texts (archaeopharmacology)
  • -Treatment of agricultural wastes for the large-scale production of high added value natural products. Focus on olive and wine industry byproducts. 
  • -Essential oils, volatile, flavor and aroma constituents

Distinctions

  • 9/2014-6/2016: Affiliate Professor, Virginia Commonwealth University, School of Medicine, Department of Physiology and Biophysics
  • 10/2013-12/2013: Visiting Professor, University of California, Davis-Olive Center
  • 1/2013-2/2013: Visiting Professor, University of California, Davis-Department of Viticulture and Enology
  • 5/2011-11/2011, Visiting Professor, University of California, Davis-Department of Environmental Toxicology
  • 2/2018: 1st award for research on olive products in OLIVE-CHALLENGE (source: SEVITEL)
  • 6/2016: Honorary Diploma for the contribution in Olive Oil research (Source: Kathimerini newspaper, Greece)
  • 6/2016: 1st Award for research related to the health protecting properties of oleocanthal (Source: Oleocanthal International Society, 3rd International Conference of OIS, Olympia 3 June 2016)
  • 2/2016:ARISTOLEO test: 1st Award for the best innovation in Greece for 2015 (Prize: 15,000 €, Source: Greek Industries Association/Eurobank)
  • 8/2014: ABB-Elsevier Investigator Award 2014 (Archives of Biochemistry and Biophysics)
  • 8/2009: Egon-Stahl Silver medal: Top scientist under 40 years old in Europe in the field of Pharmacognosy and Natural Products chemistry (Source: Society of Medicinal Plant and Natural Product Research (GA).
  • 7/1999: Travel Grant of the American Society of Pharmacognosy (5th Joint Meeting of ASP, GA, AFERP, PSE Amsterdam 1999)
  • 9/1994: 1st medal of performance and morals. Source: U. of Athens, Dept of Pharmacy.
  • 6/1994: Honorary diploma for special academic performance (1st prize). Source: 7nth Panhellenic Pharmaceutical Congress.
  • 1987: Honor in panhellenic examination in mathematics (ranked among the 15 best students in whole Greece). Source: Greek Mathematics Society

Recent publications

  • “S‐(E)‐Elenolide: a new constituent of extra virgin olive oil” A. Rigakou,  P. Diamantakos, E. Melliou and P. Magiatis,  Journal of the Science of Food and Agriculture, 2019, 99, 5319-5326.
  • “Oleocanthalic acid, a chemical marker of olive oil aging and exposure to high storage temperature with potential neuroprotective activity” A. Tsolakou, P. Diamantakos, I. Kalaboki, A. Mena-Bravo, F. Priego-Capote, A. Kaddoumi, E. Melliou, P. Magiatis. Journal of Agricultural and Food Chemistry 2018, 66 (28), 7337-7346
  •  “Effect of Olive Oil Phenolics on Lipidemic Profile and Oxidative Stress in Mice” N. Demertzis, A. Fotopoulou-Stamatelou, S. Gkinis, M. Kyriazi, E. Karalis, G.Th. Papaiwannou, E. Melliou, A. Kourounakis, P. Magiatis, H. S. Black,  M. Rallis. . J Food Nutrition Dietetics 2018, 2(1):114.
  • Cultivar influence on variability in olive oil phenolic profiles determined through an extensive germplasm survey. H. Miho, C.M. Díez, A. Mena-Bravo, V.S. de Medina, J. Moral, E. Melliou, P. Magiatis, F. Priego-Capote. Food Chemistry 2018, 266, 192-199
  • “Molecular characterization of Dalmatian cultivars and the influence of the olive fruit harvest period on chemical profile, sensory characteristics and oil oxidative stability” T. Bilušić, M. Žanetić, I. Ljubenkov, I.G. Mekinić, S. Štambuk, V. Bojović, P. Magiatis. European Food Research and Technology 2018, 244 (2), 281-289
  • “Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography–tandem mass spectrometry” V. Sánchez De Medina, H. Miho, E. Melliou, Luque De Castro, P. Magiatis, F. Priego-Capote Talanta, 2017, 162, 24-31. 
  •  “Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial” K Agrawal, E Melliou, X Li, TL Pedersen, SC Wang, P Magiatis, J. Newman. J Functional Foods 2017, 36, 84-93
  •  “Enhancement of Bioactive Phenols and Quality Values of Olive Oil by Recycling Olive Mill Waste Water” K. Kiritsakis, E. Melliou, P. Magiatis,  D. Gerasopoulos. Journal of the American Oil Chemists' Society, 1-9, 2017.
  • "Oil Quality parameters and Quantitative Measurement of Major Secoiridoid Derivatives in Neb Jmel olive oil from various Tunisian origins using qNMR and chemometric analysis" A. Ben Mansour, B. Gargouri, E. Melliou, P. Magiatis, M. Bouaziz. Journal of the Science of Food and Agriculture, 2016, 96, 4432-4439.
  • “Oleokoronal and oleomissional: new major phenolic ingredients of extra virgin olive oil” P. Diamantakos, A. Velkou, K. B. Killday, Th. Gimisis, E.Melliou, P. Magiatis. OLIVAE 2015, 122, 22-35
  • “Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers” E. Karkoula,  A. Skantzari, E. Melliou, P. Magiatis, Journal of Agricultural and Food Chemistry, 2014, 62, 600-607. 
  • “Isolation of Megaritolactones and Other Bioactive Metabolites from 'Megaritiki' Table Olives and Debittering Water” E. Mousouri, E. Melliou, P. Magiatis. Journal of Agricultural and Food Chemistry 2014, 62, 660-667. 
  • “Direct Measurement of Oleocanthal and Oleacein Levels in Olive Oil by Quantitative 1H-NMR. Establishment of a New Index for the Characterization of Extra Virgin Olive Oils” E. Karkoula,  A. Skantzari, E. Melliou, P. Magiatis, Journal of Agricultural and Food Chemistry, 2012, 60, 11696-1170 

Contact

Postal address: Section of Pharmacognosy and Natural Products Chemistry,
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 71
Athens, Greece
Tel.: +30 210 727 4052
e-mail: magiatis@pharm.uoa.gr