Proffessor, Section of Pharmaceutical Chemistry

FULL CV  

Education

• Degree in Pharmacy, Aristotles University of Thessaloniki, (1988)
• PhD, Aristotles University of Thessaloniki, (1994)
• 1994-1996 Post-doctoral training (Leiden Amsterdam Center for Drug Research, Vrije Universiteit Amsterdam, Div. of Molecular Toxicology and Pharmacology).  
• Post-doctoral training (THE HATTER CARDIOVASCULAR INSTITUTE, Research Department of Cardiovascular Medicine, Division of Medicine, University College London Hospital & Medical School), (February-March 2009)

Teaching

• Undergraduate courses: Pharmacology 1, Pharmacology 2 
• Graduate courses: in “Pharmacology”, Advanced Pharmacology
• Lectures in «Clinical Pharmaceutics», in the course “Pathophysiology, Clinical Pharmacology”  
• Lectures in “Clinical Trials, Design and Practice”, in the course “Good Clinical Practice and Regulatory Guidelines”
• Research topics
• Cardiovascular pharmacology 
• Preclinical drug and natural products screening 
• Molecular mechanism of pre- and post-conditioning strategies in the myocardium 
• Investigation of the effects of chemical substances on human physiology and investigation of the mechanisms for identification of novel therapeutic targets 
• Clinical pharmacological screening of drugs
• Molecular toxicology, cardio-oncology 

Distinctions

• 1988-1991 State Scholarship Foundation, Athens for elaboration of PhD Thesis
• 1994 Human Capital and Mobility (Leiden, the Netherlands),  post-doctoral fellowship 
• 1995 European Science Foundation (Strasburg France),  post-doctoral fellowship 
• 2007 Hellenic Society of Cardiology, for post-doctoral training in THE HATTER CARDIOVASCULAR INSTITUTE, Research Department of Cardiovascular Medicine, Division of Medicine, University College London Hospital & Medical School
• 2017 (March – June) Visiting Professor in Department of Medical Sciences, University of Turin
• Member of the Editorial Board: British Journal of Pharmacology, Basic Research in Cardiology, International Journal of Molecular Sciences, Journal of Cardiovascular Pharmacology and Therapeutics
• Guest Co-Editor: Cardiovascular Research, British Journal of Pharmacology, International Journal of Molecular Sciences
• Working Group Leader: European Network, EU-Cardioprotection
• Member of the Scientific Council for Drug Approvals [National Drug Organization (EOF)] 
• Member of the Scientific Council of Narcotics, Ministry of Health 
• Vice Chair of the Hellenic Society of Basic and Clinical Pharmacology

Recent publications

• Stamatelopoulos K, Georgiopoulos GA, Athanasouli F, Nikolaou PE, Lykka M, Roussou M, Gavriatopoulou M, Laina A, Trakada G, Charakida M, Delialis D, Petropoulos I, Pamboukas C, Manios E, Karakitsou M, Papamichael C, Gatsiou A, Lambrinoudaki IV, Terpos E, Stellos K, Andreadou I#, Dimopoulos MA#, Kastritis E#. Reactive Vasodilation Predicts Mortality in Primary Systemic Light Chain (AL) Amyloidosis. Circulation Research, 125(8):744-758, 2019. doi: 10.1161/CIRCRESAHA.119.314862. (# equally contributed senior authors)
• Efentakis P, Varela A, Chavdoula E, Sigala F, Sanoudou D, Tenta R, Gioti K, Kostomitsopoulos N, Papapetropoulos A, Tasouli A, Farmakis D, Davos CH, Klinakis A, Suter T, Cokkinos DV, Iliodromitis EK, Wenzel P, Andreadou I*. Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose dependent manner: Implications for inotropy. Cardiovascular Research, pii: cvz163. doi: 10.1093/cvr/cvz163, 2019. 
• Nikolaou PE, Boengler K, Efentakis P, Vougogianopoulou K, Zoga A, Gaboriaud-Kolar N, Myrianthopoulos V, Alexakos P, Kostomitsopoulos N, Rerras I, Tsantil-Kakoulidou A, Skaltsounis AL, Papapetropoulos A, Iliodromitis EK, Schulz R, Andreadou I*. Investigating and re-evaluating the role of GSK3beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors. Cardiovascular Research, 115, 1228–1243, 2019. 
• Efentakis P, Kremastiotis G, Varela A, Nikolaou P-E, Papanagnou E-D, Davos CH, Tsoumani M, Agrogiannis G, Konstantinidou A, Kastritis E, Kanaki Z, Iliodromitis EK, Klinakis A, Dimopoulos MA, Trougakos IP,  Andreadou I*#, Terpos E#. Molecular mechanisms of Carfilzomib-induced cardiotoxicity in mice and the emerging cardioprotective role of Metformin. Blood, 133(7):710-723, 2019. 
• Davidson SM, Ferdinandy P, Andreadou I, Bøtker HE, Heusch G, Ibáñez B, Ovize M, Schulz R, Yellon DM, Hausenloy DJ, Garcia-Dorado D. Multi-target strategies to reduce myocardial ischemia/reperfusion injury. J Am Coll Cardiol, 73(1):89-99, 2019.

Contact

Ioanna Andreadou
School of Pharmacy
Division of Pharmaceutical Chemistry
Panepistimiopolis- Zografou 157 71
Athens- Greece
Tel: 210 727-4827  Fax: 210 727-4747
E-mail: jandread[at]pharm.uoa[dot]gr