Associate Professor , Section of Pharmaceutical Chemistry

http://scholar.uoa.gr/idotsik

Education

• 1999: Degree in Pharmacy
• 2001: MSc in Pharmaceutical Analysis
• 2007: PhD in Pharmaceutical Analysis
• 2007-2011: Post-Doctoral Research in Pharmaceutical Analysis

Teaching

• Undergraduate courses/Labs: Pharmaceutical Analysis Ι & ΙΙ, Laboratory of Pharmaceutical Analysis, Stability of Pharmaceutical Products, Introduction to laboratory techniques
• Graduate courses: Advanced Pharmaceutical Analysis IΙ, Stability of Pharmaceutical Products, Statistics-Chemometrics

Research topics

• Pharmaceutical Bioanalysis 
• Drug analysis in formulations
• Neonatal screening 
• Dried Blood Spots
• Mass Spectrometry
• Chemometrics/Experimental Design (DoE)

List of recent publications

• Identification and structural characterization of potential degradation products of baricitinib using liquid chromatography combined with quadrupole time-of-flight mass spectrometry, Eleni Kakouri, Konstantinos Gkountanas, Charalabos Kanakis, Petros A. Tarantilis, Yannis Dotsikas, Acta Chromatogr. 37 (2025) 96-104
• Simulating Analyte Extraction via Sorption in Powdered and Lyophilized Pharmaceutical Products Using Butyl Rubbers Nikolaos Kritikos, Anna Bletsou, Constantinos Kousoulos, Yannis Dotsikas, Chemistry 7 (2025) 25
• A simplified metabolomic analysis of dried blood spots in breast cancer patients, Georgia Thodi, Aikaterini Triantopoulou, Aikaterini Iliou, Elina Molou, Yannis Dotsikas and Yannis L. Loukas, Scand. J. Clin. Lab. Inv. 84 (2024) 326-335
• Dried Blood Spots in Neonatal Studies: A Computational Analysis for the Role of the Hematocrit Effect, Chrysa Daousani, Vangelis Karalis, Yannis L Loukas, Kleopatra H Schulpis, Konstantinos Alexiou, Yannis Dotsikas, Pharmaceuticals 16 (2023) 1126
• Determination of bupropion and its impurities via a chaotropic chromatography method following Analytical Quality-by-Design principles for method development, Kostas Gkountanas, Anđelija Malenović, Yannis Dotsikas, Pharmaceuticals 15 (2022) 1196
• Synthesis, spectroscopic and computational evaluation of a xanthene-based fluorogenic derivatization reagent for the determination of primary amines, Amalia D. Kalampaliki, Steve Vincent, Suman Mallick, Hoang-Ngoan Le, Guillaume Barnoin, Yogesh W. More, Alain Burger, Yannis Dotsikas, Evagelos Gikas, Benoît Y. Michel, Ioannis K. Kostakis, Dyes Pigm. 196 (2021) 109798
• Achievements in robotic automation of solvent extraction and related ‎approaches for bioanalysis of pharmaceuticals Michal Alexovič, Yannis Dotsikas, Peter Bober, Ján Sabo, J. Chromatogr. Β 1092 (2018) 402-421‎
• Quantitation of brinzolamide in dried blood spots by a novel LC-QTOF-MS/MS ‎method Anargyros Foivas, Anđelija Malenović, Nađa Kostić, Marija Božić, Miroslav ‎‎Knežević, Yannis L. Loukas, Yannis Dotsikas, J. Pharm. Biomed. Anal. 119 (2016) 84-90
• ‎Liquid Chromatography coupled to Quadrupole-Time of Flight Tandem Mass ‎‎Spectrometry based Quantitative Structure-Retention Relationships of amino ‎acid ‎analogues derivatized via n-propyl chloroformate mediated reaction Nikolaos Kritikos, Anna Tsantili-Kakoulidou, Yannis L. Loukas, Yannis ‎Dotsikas, J. Chromatogr. A 1403 (2015) 70-80
• Stepwise optimization approach for improving LC-MS/MS analysis of ‎zwitterionic antiepileptic drugs with implementation of Experimental Design ‎ Nađa Kostić, Yannis Dotsikas, Anđelija Malenović, Biljana Jančić–Stojanović, ‎Tijana Rakić, Darko Ivanović and Mirjana Medenica, J. Mass Spectrom. 48 (2013) 875-884‎
• ‎Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: A worldwide collaborative project D. M. McHugh, C. A. Cameron, J. E. Abdenur, M. Abdulrahman, et al., Genet. Med. 13 (2011) 230-254

Contact

Dotsikas Yannis (Ioannis)
School of Pharmacy
Division of Pharmaceutical Chemistry
Panepistimiopolis- Zografou 157 71
Athens- Greece
Tel: 210 727-4696  210 727-4039
E-mail: idotsik@pharm.uoa.gr