Professor, Pharmaceutical Nanotechnology

Director in the Laboratory of Pharmaceutical Technology, Faculty of Pharmacy

National and Kapodistrian University of Athens President of Hellenic Pharmaceutical Society (HPS) Member of the Executive Committee of European Federation of Pharmaceutical Sciences (EUFEPS) 2014-today Department of  Pharmaceutical Technology

Award Academy of Athens 2018


Research Group




  • 1983 Diploma (M. Pharm.), Faculty of Pharmacy, Graduated Pharmacist, National & Kapodistrian University of Athens, Greece 
  • 1985 License of Pharmaceutical profession, Ministry of Health, Athens, Greece. 
  • 1990 Ph.D. in Pharmaceutical Sciences, National & Kapodistrian University of Athens 
  • Postdoctoctoral, University of California, San Francisco U.S.A. Department of Cellular and Molecular Pharmacology, Cancer Research Institute (Pharmaceutical Nanotechnology, Drug Delivery Systems).
  • Training on Advanced Program Thermal Analysis Seminars for DSC (Differential Scanning Calorimetry), and for TGA (Thermogravimetric Analysis) in METTLER-TOLEDO (Switserland, Zurich, September 2003). 
  • Training on Advanced Thermal Analysis Techniques, University of DiSTAM, Milan, Italy


Undergraduate courses/labs: 

  • 2003-to date.   Teaching ‘Pharmaceutical Technology- Physical pharmacy and Pharmaceutical Nanotechnology ‘, semester 5th 
  • 2003-to date. Teaching ‘Regulatory affairs in Pharmaceutical Industry and in Pharmaceutical Products’, semester 9th. 
  • 2004-to date. Participation in laboratory exercises of Pharmaceutical Technology, semester 7th
  • 2015-to date. Teaching ‘Innovative Pharmaceutical formulations’, semester 9th, Faculty of Pharmacy.
  • 2017 and 2019 -to date. Teaching ‘Precise Nanomedicine’ as visiting Professor in The School of Medicine in the National & Kapodistrian University of Athens, Greece and in The school of Medicine in the University of Thessalia, Greece.

Graduate courses: 

  • 2003-to date.  Teaching in ‘Industrial Pharmacy / Physical Pharmacy’. 
  • 2015-to date.  Teaching in ‘Cosmetics. Innovative products’
  • 2018-to date.  Teaching in ‘Nanomedicine’ an International master’s degree course
  • 2019 -to date. Teaching in ‘Development of new medicines‘master’s degree course.

Research topics

  • Preparation of nanoparticulate systems such as, liposomes, dendrimers, solid lipid nanoparticles, nanoemulsions and nanosystems encapsulating drugs or potentially biological active compounds (peptides, proteins, active macromolecules etc); physicochemical characterization; in vitro and in vivo studies: advanced drug delivery nano systems and fractal analysis of their morphology. 
  • Physical Pharmacy. Thermal Analysis (DSC) studies on lipid bilayers interactions with biologically active compounds, RAMAN spectroscopy, 13C NMR,  SEM, TEM and AFM studies in collaboration with National and European partners. 


  • Award from the Academy of Athens, 2018 for his achievements (innovation and interdisciplinarity) in Pharmaceutical nanotechnology and for his exquisite monograph ‘Pharmaceutical Nanotechnology. Fundamentals and practical applications’, Springer, 2016.
  • Awards in International and National Scientific Congresses
  • President or member in International and National scientific congresses and committees, respectively.
  • Member of the Executive Committee (ExCo) of National Medicines Agency (2010-2013).
  • Member of the Editorial board of National and International Scientific journal 
  • Guest Editor of Journal of Thermal Analysis and Calorimetry in the special issue of “The Application of Thermal Analysis in Pharmaceutical Sciences” 
  • Honorary reference in the series of books ‘Topics in thermal Analysis and Calorimetry’, Vol. 10, Springer, 2014
  • Special Reference of the scientific journal of “Who is publishing in my domain” journal (WiPiMD) for the publication of the review paper entitled: “Differential Scanning Calorimetry (DSC): a tool to study the thermal behavior of lipid bilayers and liposomal stability. C. Demetzos, J. Liposome Res.; 2008; 18(3):159-73. 
  • Member of the Management Committee of COST Action “Dendrimers in biomedical applications” 
  • Editor of the Greek Edition of Journal of Medical Association (JAMA) (2004-2006) 
  • President of the Hellenic Pharmaceutical Society (HPS) since 2008
  • Founder and Deputy Director of the postgraduate Master program which leads to the award of a Master degree in ‘NANOMEDICINE’

Recent publications

  • More than 250 published papers and 400 presentations (oral or poster) in International Journals, Book series, and in International and National scientific congresses, respectively. Based on Google scholar h index 46; i10-index 136.


  • Costas Demetzos, Scientific Custody of the Greek edition of the handbook”Physical Pharmacy” A.T.Floerence and D. Attwood, Ed. Parisianos, S.A, 2014, Athens
  • Costas Demetzos, Scientific Custody of the Greek edition of the handbook “Chemical Thermodynamics. At a Glance”, H.D.B. Jenkins. Ed. Parisianos S.A, 2015, Athens
  • Costas Demetzos,  Scientific Custody of the Greek edition of the handbook ”Pharmeceutics. Drug Delivery and Targeting.” Y. Periee and T. Rades, Ed. Parisianos, S.A, 2015, Athens
  • Costas Demetzos and E. Papadimitriou, Scientific Custody of the Greek edition of the handbook ‘Remington: An Introduction to Pharmacy’, Ed. By L.V.Allen, Greek Edition, Parisianos S.A, 2019, Athens
  • Costas Demetzos, Stergios Pispas, Natassa Pippa Eds in ‘Drug delivery Nanosystems. From Bioinsporation and Biomimetics to clinical Applications’ Pan Stanford, 2018
  • Costas Demetzos, Natassa Pippa Eds, in ‘Thermodynamics and Biophysics in Biomedical Nanosystems: Applications and practical considerations’ Springer, 2019
  • Costas Demetzos , Natassa Pippa Eds, in ‘Nanomaterials for clinical applications : case studies in nanomedicines’ Elsevier, 2019


  • Costas Demetzos: Physical, Chromatographic and Spectroscopic methods of Analysis of Natural Products. University of Athens, Athens, 105 pages, 2001. 
  • Costas Demetzos Pharmaceutical Technology (Physical Pharmacy), University notes, Athens, 130 pages, 2003
  • Costas Demetzos, Monograph on ‘Pharmaceutical Nanotechnology: Basic principles and Practical Applications’, 400 pages, Ed. Parisianou 2015, Athens, Textbook in National Universities
  • Costas Demetzos , Monograph on ‘The Sound of Science and the Silence of Nature’, Parisianou S.A, 2019, pages 235, 


  • Costas Demetzos, Monograph on ‘Pharmaceutical Nanotechnology: Fundamental and Practical Applications’, Springer 2016. The monograph was inclusive textbook appropriate to be disseminated to students enrolled to the master program ‘Nanomedicine’.     


  • Cubic lyotropic liquid crystals as drug delivery systems: Physicochemical and Morphological studies. M. Chountoulesi, N. Pippa, S. Pispas, E. D. Chrysina, M. Libera, B. Trzebicka, C. Demetzos, Int. Journal of Pharmaceutics, 550 (1-2): 57-70, 2018

  • Physicochemical Study of the Protein-Liposome Interactions: Influence of Liposome Composition and Concentration on Protein Binding, F. Papageorgiou, N. Pippa, N. Naziris, C. Demetzos, J. Liposome Res., 2018 Apr 24:1-29, 2018.
  • Studying the colloidal behavior of chimeric liposomes by cryo-TEM, micro-differential scanning calorimetry and high-resolution ultrasound spectroscopy. N. Pippa, D. R. Perinelli, S. Pispas, G. Bonacucina, C. Demetzos, A. Forys, B. Trzebicka, Colloids and Surfaces A,Physicochemical and Engineering Aspects, 555: 539-547, 2018.
  • Hydrogels as intelligent drug delivery systems. N. Pippa, N. Bouropoulos, S. Pispas, C. Demetzos, A. Papalois in: ‘Drug delivery Nanosystems. From Bioinsporation and Biomimetics to clinical Applications’ Eds. C. Demetzos, S. Pispas, N. Pippa, Springer, 2018, Pan Stanford, 2018
  • Introducing thermodynamics and biophysics in Health Sciences? C. Demetzos, N. Pippa, in: ‘Thermodynamics and Biophysics in Biomedical Nanosystems: Applications and practical considerations’ Eds. C. Demetzos, N. Pippa, Springer, 2019
  • Differential scanning calorimetry (DSC): an invaluable tool for the thermal evaluation of advanced chimeric liposomal drug delivery nanosystems. M. Chountoulesi, N. Naziris, N. Pippa, S. Pispas, C. Demetzos in: ‘Thermodynamics and Biophysics in Biomedical Nanosystems: Applications and practical considerations’ Eds. C. Demetzos, N. Pippa, Springer, 2019
  • pH-responsive polymeric nanoassemblies encapsulated into alginate beads: morphological characterization and swelling studies, N. Pippa, A. Papalois, S. Pispas, C. Demetzos, N. Bouropoulos, J. of Polymer Res, 25:117, 2018


Postal address: Section of Pharmaceutical Technology,
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 84
Athens, Greece
Tel.: +30(210) 7274596
Fax: +30(210) 7274027