Professor, Section of Pharmaceutical Technology

Education

• Degree in Physics (University of Athens, 1996)
• MSc in Physics (University of Athens, 1999)
• PhD in Pharmacy (University of Athens, 2002)

Teaching

Undergraduate courses/labs:

• General Mathematics
• Introduction to Programming and Computational Applications
• Biopharmaceutics – Pharmacokinetics I
• Biopharmaceutics – Pharmacokinetics II
• Laboratory of Biopharmaceutics – Pharmacokinetics
• Introduction to Laboratory Practices

Graduate courses: 

• Advanced Biopharmaceutics – Pharmacokinetics (MSc Industrial Pharmacy)
• Applications of Statistics to Pharmaceutical Sciences (MSc Industrial Pharmacy)
• Laboratory Exercises in Industrial Pharmacy (MSc Industrial Pharmacy)
• Application of Pharmacokinetics to Therapeutics (MSc Clinical Pharmacy)
• Pharmacometrics (MSc Biostatistics), 

Research topics

• Model Informed Drug Development (MIDD)
• Quantitative Clinical Pharmacology
• Physiologically Based Pharmacokinetic Models (PBPK)
• Mathematical Pharmacology

Distinctions

• Member of the Modelling and Simulation Working Party (MSWP) of the European Medicines Agency (2016-now)
• Member of the Editorial Board of the Journal of Pharmacokinetics and Pharmacodynamics (2011-now)

Recent publications

• Karakitsios E, Dokoumetzidis A. Extrapolation of lung pharmacokinetics of antitubercular drugs from preclinical species to humans using PBPK modelling. J Antimicrob Chemother. 79(6):1362-1371. doi: 10.1093/jac/dkae109. (2024a)
• Kaikousidis C, Bies RR, Dokoumetzidis A. Simulating realistic patient profiles from pharmacokinetic models by a machine learning postprocessing correction of residual variability. CPT Pharmacometrics Syst Pharmacol. doi: 10.1002/psp4.13182.  (2024b)
• Karakitsios E, Dokoumetzidis A. A meta-analysis methodology in Stan to estimate population pharmacokinetic parameters from multiple aggregate concentration-time datasets: application to gevokizumab mPBPK model. Pharmaceutics 16(9), 1129. doi: 10.3390/pharmaceutics16091129 (2024c)
• Seliniotaki AK, Lithoxopoulou M, Virgiliou C, Gika H, Dokoumetzidis A, Bougioukas KI, Raikos N, Diamanti E, Ziakas N, Haidich AB, Mataftsi A. Efficacy and safety of mydriatic microdrops for retinopathy of prematurity screening. JAMA Ophthamology 143(2):110-116. doi: 10.1001/jamaophthalmol.2024.5462 (2025a)
• Karakitsios E, Angelerou M, Kapralos I, Tsakiridou G, Kalantzi L, Dokoumetzidis A. Integrating In Vitro Dissolution and Physiologically Based Pharmacokinetic Modeling for Generic Drug Develop-ment: Evaluation of Amorphous Solid Dispersion Formulations for Tacrolimus. Pharmaceutics 17(2), 227. doi: 10.3390/pharmaceutics17020227 (2025b)
• Athanassa Z, Papakyriakopoulou P, Marquez Megias S, Saitani EM, Manioudaki S, Dimoula K, Petsa I, Valsami G, Sakagianni A, Koumaki V, Dokoumetzidis A, Tsakris A. Population Pharmacokinetic Model of Oral Minocycline in Critically Ill Adult Patients with ventilator-associated pneumonia. J Antimicrob Chemother. doi: 10.1093/jac/dkaf090 (2025c)
• Karakitsios E, Della Pasqua O, Dokoumetzidis A. Extrapolation of lung pharmacokinetics of bedaquiline across species using physiologically-based pharmacokinetic modelling. Br J Clin Pharmacol. doi: 10.1002/bcp.70163. (2025d).

Contact

Postal address: Section of Pharmaceutical Technology
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 84
Athens, Greece
Tel.: +30(210) 7274122
e-mail: adokoum@pharm.uoa.gr