VLACHOU MARILENA

Associate Professor, Section of Pharmaceutical Technology

 

 

 

Education

  • Degree: BSc in Pharmacy. National and Kapodistrian University of Athens (NKUoA), Greece
  • PhD in Pharmaceutical Technology, National and Kapodistrian University of Athens (NKUoA), Greece

Teaching

Undergraduate courses/labs 

  • Co-teaching of the compulsory course "Pharmaceutical Technology I" to the students of the 5th semester of the undergraduate programme of the Department of Pharmacy of the University of Athens (1994-present).
  • Co-teaching of the elective course "Modern Pharmaceutical Systems" to the students of the 8th semester of the undergraduate programme of the Department of Pharmacy of the University of Athens (2015-present).
  • Participation in the laboratory practicals of the course "Pharmaceutical Technology" (1994 - today, as a faculty member).
  • Supervision of the laboratory practicals of the undergraduate students of the School of Pharmacy, University of Rhode Island (U.R.I., U.S.A.) (1989).

Graduate courses

  • Co-teaching of the compulsory course "Physical Pharmacy" (Module: Industrial Pharmacy (1994 - today)).
  • Participation in the teaching of the seminar course "Cosmetology-Dermatopharmacology" (2016-).
  • Co-teaching of the compulsory course "Nanomedicine" (Module: Application of Nanotechnology in Medicine (2018 - ).
  • Joint organization and teaching of the compulsory course "Development of new drugs: Research, circulation and accessibility" (Module: Development of drug controlled release systems (2019 - ).

Research topics

  • formulation and "in vitro" release studies of bioactive substances from topical formulations.
  • controlling the efficacy and safety of formulations in skin disease therapies.
  • modified release studies on novel pyrrolinoquinoline derivatives, with cytotoxic activity, from solid formulations.
  • physicochemical properties of new excipients (Ulvans) and their application in the manufacture of solid pharmaceutical formulations, and of nanoparticulate substrates as active substance carriers for the study of their release.

Distinctions

  • Designated Postgraduate Scholarship (Ε.Μ.Υ.) awarded by the Division of Pharmaceutical Technology (NKUoA).

Recent publications

  • Zampakola, A. Siamidi, N. Pippa, C. Demetzos, M. Vlachou. Chronobiotic Hormone Melatonin: Comparative in vitro Release Studies from Matrix Tablets and Liposomal Formulations Lett Drug Des Discov, 14(4), 476-480, (2017). DOI: 10.2174/1570180813666161006162246
  • M. Vlachou, A. Siamidi, E. Diamantidi, A. Iliopoulou, I. Papanastasiou, V. Ioannidou, V. Kourbeli, A.-S. Foscolos, A. Vocat, S.T. Colec, V. Karalis, T. Kellici, T. Mavromoustakos. In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I) Drug Res, 67(8), 447-450, (2017). DOI: 10.1055/s-0042-121491 (2017) 
  • M. Vlachou, A. Siamidi, D. Spaneas, D. Lentzos, P. Ladia, K. Anastasiou, I. Papanastasiou, A-S. Foscolos, M-O. Georgiadis, V. Karalis, T. Kellici, T. Mavromoustakos. In vitro Controlled Release of two new Tuberculocidal Adamantane Aminoethers from Solid Pharmaceutical Formulations (II). Drug Res, 67(11), 653-660, (2017). DOI: 10.1055/s-0043-114012
  • M. Vlachou, M. Papamichael, A. Siamidi, I. Fragouli, P. A. Afroudakis, R. Kompogennitaki Y. Dotsikas. Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes. Int J Mol Sci 18, 1641, (2017). DOI: 10.3390/ijms18081641
  • M. Vlachou, K.Tragou, A. Siamidi, S. Kikionis, A. L. Chatzianagnostou, A. Mitsopoulos, E. Ioannou, V. Roussis, A. Tsotinis. Modified in vitro release of the chronobiotic hormone melatonin from matrix tablets based on the marine sulfated polysaccharide ulvan. J Drug Deliv Sci Technol 44, 41- 48, (2018). DOI: 10.1016/j.jddst.2017.11.019
  • M. Vlachou, S. Kikionis, A. Siamidi, K. Tragou, E. Ioannou, V. Roussis, A. Tsotinis. Modified in vitro release of melatonin loaded in nanofibrous electrospun mats incorporated into mono-layered and three-layered tablets. J Pharm Sci 108(2), 970-976, (2019). DOI: doi.org/10.1016/j.xphs.2018.09.035
  • M. Vlachou, S. Kikionis, A. Siamidi, K. Tragou, S. Kapoti, E. Ioannou, V. Roussis, A. Tsotinis. Fabrication and Characterization of Electrospun Nanofibers for the Modified Release of the Chronobiotic Hormone Melatonin. Curr Drug Deliv, 16(1), 79-85 (2019). DOI: 10.2174/1567201815666180914095701.
  • M. Vlachou, A. Siamidi, Y. Dotsikas. Desirability based optimization of Mesalazine modified release formulations: mini tablets in capsules and compression coated tablets. Lett Drug Des Discov, 16, (2019). DOI.10.2174/1570180816666190110125812
  • E. Kotroni, E. Simirioti, S. Kikionis, I. Sfiniadakis, A. Siamidi, V. Karalis, A. Vitsos, M. Vlachou, E. Ioannou, V. Roussis, M. Rallis. In vivo evaluation of the anti-inflammatory activity of electrospun micro/nanofibrous patches loaded with Pinus halepensis bark extract. Materials, 12, 2596, (2019) DOI:10.3390/ma12162596
  • A. Papageorgiou, A-S Foscolos, I. Papanastasiou, M. Vlachou, A. Siamidi, A. Vocat, S.T. Cole, T. Kellici, T. Mavromoustakos, A. Tsotinis. Design, Synthesis, Biology, Computational Studies and in vitro Controlled Release of new Isoniazid-based Adamantane Derivatives with Antitubercular Activity. Future Μed Chem, 65, (2019). DOI: 10.4155/fmc-2019-0038 
  • M. Vlachou, S. Kikionis, A. Siamidi, S. Kyriakou, A. Tsotinis, E. Ioannou, V. Roussis Development and Characterization of Eudragit®-based Electrospun Nanofibrous Mats and their Formulation into Nanofiber Tablets for the Modified Release of Furosemide. Pharmaceutics, 11(9), 480-93, (2019). DOI:10.3390/pharmaceutics11090480
  • M. Vlachou, I. Papanastasiou, M.O. Georgiadis, A. Tsakoumagkou, Z. Siskos, A. Siamidi, A. Konstantinou, A. Vocat, S. T. Cole. Design, Synthesis and in vitro Controlled Release of new Adamantanodiarylketone Antimycobacterials. ChemistrySelect, 4, 11048-11051, (2019). DOI: 10.1002/slct.201902283


Contact

Postal address: Section of Pharmaceutical Technology,
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 84
Athens, Greece
Tel.: +30(210) 727 4674
Fax: +30(210) 727 4674
e-mail: vlachou@pharm.uoa.gr