Associate Professor,  Section of Pharmacognosy and Natural Product Chemistry

FULL CV

Education

• B.Sc. in Agricultural Biotechnology, Department of Agricultural Biotechnology, Agricultural University of Athens (07/2003)
• M.Sc. in Pharmacognosy and Chemistry of Natural Products, Section of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens (11/2005)
• Ph.D. in Pharmacy, Section of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens (03/2009)
• Postdoctoral Research, Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California – San Diego, U.S.A. (09/2009–06/2010)

Teaching

• Undergraduate courses/labs: Pharmacognosy III, Pharmacognosy II Labs
• Graduate courses: Marine Pharmacognosy and Synthesis of Natural Products, Introduction to Good Laboratory Practice, Bioactive Natural Products, Spectroscopy ΙΙ, Bibliographic Search on Specialized Topics, Management of the Marine Environment, Natural Products from Marine Organisms and their Applications

Research topics

• Isolation and structure elucidation of natural products from marine and terrestrial macroorganisms aiming at the assesement of their biological activity or their ecological role.
• Isolation of symbiotic, endophytic, epiphytic or / and free-living bacteria and fungi from the marine environment aiming at the isolation of bioactive metabolites.
• Development of methodology based on LC-DAD-MS, GC-MS and NMR and construction of in-house databases aiming at the metabolomic fingerprinting of marine organisms.
• Bioconversions of bioactive secondary metabolites by marine-derived microorganisms aiming at the production of analogues and their biological activity evaluation thereof.

Distinctions

• Scholarship of high academic performance during Junior and Senior High School (Pierce College, 1990–1996)
• Award of high academic performance during postgraduate studies (State Scholarships Foundation, 2004–2005)
• Scholarship for postdoctoral research (PNG Gerolymatos, 2009–2011)
• Regional Representative of the Phytochemical Society of Europe (PSE) for South-East Europe (06/2011–03/2015) and Meetings’ Secretary (07/2017-present)

Recent publications

• Perdikaris S., Mangoni A., Grauso L., Papazafiri P., Roussis V., Ioannou E. Vagiallene, a rearranged C15 acetogenin from Laurencia obtusa. Org. Lett., 2019, 21, 3183-3186.
• Lefranc F., Koutsaviti A., Ioannou E., Kornienko A., Roussis V., Kiss R., Newman D. J. Algae metabolites: from in vitro growth inhibitory effects to promising anticancer activity. Nat. Prod. Rep., 2019, 36, 810-841.
• Tziveleka L.A., Ioannou E., Roussis V. Ulvan, a bioactive marine sulphated polysaccharide as a key constituent of hybrid biomaterials: A review. Carbohydr. Polym., 2019, 218, 355-370.
• Daskalaki M. G., Vyrla D., Harizani M., Doxaki C., Eliopoulos A. G., Roussis V., Ioannou E., Tsatsanis C., Kampranis S. C. Neorogioltriol and related diterpenes from the red alga Laurencia inhibit inflammatory bowel disease in mice by suppressing M1 and promoting M2-like macrophage responses. Mar. Drugs, 2019, 17, 97.
• Tziveleka L.A., Pippa N., Georgantea P., Ioannou E., Demetzos C., Roussis V. Marine sulfated polysaccharides as versatile polyelectrolytes for the development of drug delivery nanoplatforms: Complexation of ulvan with lysozyme. Int. J. Biol. Macromol., 2018, 118, 69-75.
• Rab E., Kekos D., Roussis V., Ioannou E. α-Pyrone polyketides from Streptomyces ambofaciens BI0048, an endophytic actinobacterial strain isolated from the red alga Laurencia glandulifera. Mar. Drugs, 2017, 15, 389.
• Dimou Μ., Ioannou Ε., Daskalaki M.G., Tziveleka L.A., Kampranis S.C., Roussis V. Disulfides with anti-inflammatory activity from the brown alga Dictyopteris membranacea. J. Nat. Prod., 2016, 79, 584–589.
• Ignea C., Athanasakoglou A., Ioannou E., Georgantea P., Trikka F.A., Loupassaki S., Roussis V., Makris A.M., Kampranis S.C. Carnosic acid biosynthesis elucidated by a synthetic biology platform. Proc. Natl. Acad. Sci. USA, 2016, 113, 3681–3686.

Contact

Postal address: Section of Pharmacognosy and Chemistry of Natural Products,
Department of Pharmacy,
National and Kapodistrian University of Athens,
Panepistimiopolis, 157 71
Athens, Greece
Tel.: +30 210 727 4913
Fax: +30 210 727 4592
e-mail: eioannou@pharm.uoa.gr