Compulsory / Teaching hours per week: 3 / Laboratory hours per week: 3 /Assessment: final exam at the end of each term or September/ Credits: 5
Vassili Kouvelis, Assist. Professor
Panagoula Kollia, Professor
Maria Sarika, EDIP
Claudia Gementzi, EDIP
• The Chemistry of Life (1 Hour): Atoms, bonds and simple molecules. The biological importance of water. Carbohydrates, Lipids, Proteins, Nucleic acids.
• The Cell - Structure and Function (3 Hours): Biological Membranes: Structure and Function. Organelles. Cytoskeleton.
• Energy and Metabolism – Cellular Respiration (3 Hours): Forms of Energy - Energy Transformations. The Laws of Thermodynamics. Free Energy, ATP and cellular work. Enzymes. ATP production. Glycolysis, cycle of Krebs, oxidative phosphorylation. Fermentation.
• Cell Cycle and Cell Division (3 Hours): Mitosis. Regulators of Cell Cycle Progression.
• Meiosis (3 Hours): Mechanism. Oogenesis. Spermatogenesis. Artificial Reproduction.
• Introduction to Genetics (3 Hours): Mendelian Laws. Chromosomal Theory of Inheritance. Genetic recombination. Gene mapping.
• From Nucleic acids to Proteins (9 Hours): Replication. RNA synthesis (Transcription). Protein Synthesis (Translation). The Genetic Code. Repair mechanisms.
• Viruses (1 Hour): Structure and reproduction. Viroids. Prions.
• Biotechnology and Recombinant DNA Technology (3 Hours): Restriction enzymes, Cloning. DNA vectors. Selection of transformed cells. Study of Human Genome and Modern Medicine. Subjects of Moral Safety.
• Genetic Diseases – Chromosomal Mutations (3 Hours). Karyotype, chromosomal abnormalities, chromosomal syndromes.
• Genetic Diseases – Blood Disorders (3 Hours). Abnormal hemoglobin production, sickle cell anaemia, thalassemia.
• Pharmacogenomics (3 Hours). Applications of knowledge to human genome, pharmacogenomics.
Topics of Laboratory Exercises
• Microscopy - Cellular Division: Mitosis - Meiosis.
• DNA Isolation.
• Blood, blood cell types, blood typing.