(Elective / Teaching hours per week: 3 / Assessment: final exam at the end of each term or September/ Credits: 3)
Teachers:
C. Reppas (Professor), G. Valsami (Professor), M. Symillidou (Associate Professor), M. Vertzoni (Assistant Professor)
Topics:
- Introduction
- Single dose administration - Two compartment open model: iv bolus injection
- Repeated dose administration-Non-compartmental analysis: Superposition
- Repeated dose administration - One compartment open model: iv bolus and per os administration
- Distribution of drugs into the Central Nervous System
- Biopharmaceuticals: Basic concepts and Pharmacokinetic / Pharmacodynamic issues
- Pharmacokinetic – Pharmacodynamic modelling: Basic concepts
- Drug absorption after per os administration to children: population, products, GI physiology in children, food effect on absorption, clinical studies
- Drug absorption after per os administration to the elderly: GI physiology in the elderly and effect on drug absorption
- Non-oral extravascular administration of drugs: Oral inhalation, nasal, oral cavity, transdermal, intramuscular, rectal, vaginal, ocular