(Elective / Teaching hours per week: 4 / Assessment: final exam at the end of each term or September– lab work paper/ Credits: 4 )
Teachers:
Sophia Mitakou, Professor
Nektarios Aligiannis, Associate Proffesor
Halabalaki Maria Assistant Professor
Topics:
- Extraction and Isolation with modern extraction techniques (Accelerated Solvent Extraction, Supercritical Fluid Extraction, Subcritical Water Extraction and Microwave Assisted Extraction).
- Applications of Centrifugal Partition Chromatography and the use of adsorption resins (Adsorption Resin Technology).
- Automated Medium Pressure Liquid Chromatography (MPLC) and Preparative High Pressure Liquid Chromatography (HPLC) techniques.
- Application of analysis techniques for the characterization of the metabolic profile and the metabolic fingerprinting of total extracts and pure molecules.
- Coupled technique LC-MS and LC-MS / MS and its application in the analysis of extracts and mixtures of natural origin.
- Structure determination of natural compounds (flavonoids, alkaloids, coumarins, phenolic acids, lignans, sugars) through the study of their spectroscopic data: Mass spectrometry (MS), Infrared (IR), Nuclear and Magnetic Resonance Spectroscopy (NMR).